Achieving and maintaining viral suppression can help decrease HIV-associated complications, prevent development of drug resistance, and prevent transmission. Regimens with simple administration, including low pill burden and no food requirement, help improve treatment adherence. Additionally, single-tablet regimens (STRs) minimize the possibility of selective noncompliance and the risk of patients taking an incomplete regimen.

Patients need to take their medication every day as prescribed to achieve virologic suppression. Side effects of patients’ treatment can lead to discontinuation or altering of therapy. Management strategies must be individualized for each patient.